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KMID : 0922220100100010059
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Journal of the Korean Musculoskeletal Transplantation Society
2010 Volume.10 No. 1 p.59 ~ p.65
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The Role of Demineralized Bone Matrix as a Bone Graft Enhancer in Spinal Fusion
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Yoo Byeong-Wook
Kim Jong-Heon
Kim Jae-Hoon
Park Ye-Soo
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Abstract
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Purpose: We used demineralized bone matrix (DBM) and local laminar bone gathered for decompression procedure with or without autogenous iliac bone in posterolateral lumbar fusion and compared with cases that used with autogenous iliac bone and local laminar bone to evaluate the efficacy of DBM as bone graft extensor or inhancer.
Materials and Methods: From May 2004 to March 2006, 83 patients who got posterolateral lumbar fusion were included. DBM with small amount of iliac bone and local bone were used in 12 patients (group I), and DBM with local bone only in 54 patients (group II). In 17 patients, iliac bone and local bone were used for fusion. After the evaluation of fusion rate of each group with Lenke classification and Glassman classification using simple radiograph and CT, the fusion rates of group I with III and group II with III were compared respectively.
Results: In Lenke classification, the percentages of A, B, C and D were 58.4%, 25.0%, 8.3% and 8.3% in group I, 51.9%, 11.1%, 18.5% and 18.5% in group II, and 64.7%, 11.8%, 23.5% and 0% in group III. There were no significant differences in fusion rates between group I and III by Lenke and Glassman classification (p=0.37, 0.51) nor in fusion rates between group II and III (p=0.3, 0.44).
Conclusion: DBM seems to have a role as bone graft extender in posterolateral fusion of lumbar spine, and it needs to study further for evaluation of the role as bone graft enhancer.
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KEYWORD
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Spinal fusion, Graft enhancer, Graft extensor, Demineralized bone matrix
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